Ayahuasca: Beyond the brew
Ayahuasca can offer deep transformation, but it requires careful consideration. Whether you’re a curious explorer, a therapist, or yearning for healing, clarity or insights, understanding the full scope of this sacred brew can be extremely helpful.

Ayahuasca is not merely a transformation tool, but a sacred plant teacher and tradition that connects participants to eclectic spiritual wisdom, plant intelligence, and communal ritual practices that have evolved through South American lineages for generations.

AYAHUASCA.nexus serves as a guide for those seeking to understand more; traditional origins, contemporary practices, potential benefits, scientific facts and important safety considerations. Our aim is to honor plant and ancient wisdom while providing balanced, responsible information for those called to this path.


Ayahuasca, is it calling you?
A 25-question assessment helps you explore your mindset and 'readiness', discovers your preparedness for this inner journey, and provides you with a personalised report across:

Inner calling & motivation: Uncover your unique purpose and intentions

Emotional readiness: Your ability to navigate deep emotions

Practical preparation: Ensure you are prepared for the full experience

Psychological & ego strength: Can you stay grounded through profound transformation?

Ayahuasca's dimensions
Ayahuasca exists at the intersection of biochemistry, indigenous knowledge, and cultural practice and has gained global attention for its perceived profound effects on consciousness. We explore three fundamental dimensions of ayahuasca: its physical nature, its role in knowledge transmission, and its place within evolving traditions.
A sacred brew
A botanical preparation of one or multiple plant species, creating a unique embodied interaction that temporarily alter consciousness and perception. Ayahuasca can provoke a reconnection of body, mind, and spirit, transcending mere biochemical effects.
A living (plant) teacher
With ayahuasca, you enter a potential transformative relationship, guided by a plant recognized not only for personal insight but as a sentient carrier of ancestral wisdom. In most contexts, ayahuasca is approached as a conduit of knowledge, offering insights through direct experience and revealing perspectives beyond ordinary awareness.
An evolving tradition with ancient roots
A tradition that continues to adapt and evolve, connecting participants to eclectic spiritual wisdom, ecological consciousness, and communal ritual practices that have developed through South American lineages for generations.
Receive the latest insights on ayahuasca — research, integration, and meaningful developments.
Just what’s worth knowing.

Ayahuasca: Essential considerations
Safety & Care
Prioritizing wellbeing before, during, and after your experience. Understanding contraindications, proper screening, and ensuring qualified facilitation is essential for minimizing risks. Safety includes choosing facilitators with authentic experience and connection to their tradition—this protects both you and the integrity of their tradition.
Set & Setting
Your mindset, physical environment, and preparation significantly impact your experience. Consider your intentions, the ceremonial space, and the context in which you participate. Your mindset could include gratitude toward the traditions who preserved and shared these practises and humility about your role as a participant in sacred ceremonies.
Integration
The process of making meaning from your experience and incorporating insights into daily life. Integration extends far beyond the ceremony and often determines the lasting value of your encounter with ayahuasca. Integration includes considering how the improved quality of your life could contribute beyond yourself—whether through supporting the original communities that preserve these practices, rainforest protection, or service to others.

Key aspects of the ayahuasca journey
Embarking on an ayahuasca journey is more than a weekend retreat—it’s a profound rite of passage that invites you to explore the deepest layers of body, mind, and spirit. To help you prepare, navigate, and integrate this experience safely and meaningfully, here’s a comprehensive roadmap divided into three essential phases: Preparation, Ceremony, and Integration.
1. Preparation: Setting the stage
a. Understand what ayahuasca is
Before participating, take time to educate yourself about ayahuasca—its origin, how it works, and the effects it can have, both positive and challenging.


b. Choose wisely
Drink only with a trustworthy facilitator, shaman, or retreat centre—ideally through direct personal referrals, not just online reviews. A reliable provider will offer clear pre-ceremony guidance and conduct a thorough medical assessment. Most importantly, they won’t try to convince or advise you to drink ayahuasca. The choice should always be yours.

Be mindful of anyone making promises of healing, visions, or specific outcomes. A grounded retreat honours the mystery of the process and avoids claims it cannot guarantee. Facilitators who are true to themselves—and to the people they welcome—create space; they don’t promise results.


c. Know what you drink
Inform yourself about the source and composition of the brew. The distinction between traditional ayahuasca and 'anahuasca' (analogous brews made with non-traditional plants) is especially relevant outside South America, where local or even synthetic substitutes are sometimes used—occasionally without full disclosure.

Be especially cautious with added plants like datura, which may induce intense experiences but can also be physically and psychologically harmful. A trustworthy facilitator will be transparent about the ingredients and their origins.


d. Your medical history
Be open about any medications or health conditions, both physical and mental. Ayahuasca can interact dangerously with certain substances and conditions—especially SSRIs, MAOIs, stimulants, heart issues, high blood pressure, or a personal or family history of psychosis.

Before making travel plans, make sure ayahuasca is safe for you. Any responsible retreat center will include a proper medical assessment. If you’re unsure, consult with a healthcare provider who understands both ayahuasca and your medical background.


e. Follow the recommended preparation guidelines
Respect the preparation guidelines given by your facilitator or retreat centre. These often include avoiding alcohol, recreational substances, certain foods, and intense stimulation in the days around the ceremony. This helps your body and mind become more open and receptive.


f. Traditional dieta or gentle cleanse
A traditional dieta—usually 3 to 7 days of avoiding salt, sugar, caffeine, alcohol, red & pig meat, and sexual activity—is meant to calm the system and heighten inner awareness. If that feels too intense, a lighter 'cleanse' can still help: eat simple, plant-based meals, stay hydrated, eat early, get proper sleep, and reduce screen time and overstimulation.


g. Mental & emotional preparation
Reflect on why you are drawn to this experience. A clear, honest intention can anchor and guide you during the ceremony and beyond. This intention might be a question, a theme, or even a gentle request to the plant itself—such as: 'Show me what I need to learn.' You might also take time to notice the different voices or feelings within you—some curious, some cautious, some perhaps seeking clarity or healing. Simply acknowledging these parts, without trying to change them, can bring a sense of calm and inner coherence.

In the days leading up to the retreat, prepare your emotional and mental space. Practices like meditation, journaling, quiet time in nature, or talking with someone you trust can help you arrive with more calm, presence, and openness—and support you in staying grounded throughout the process.


h. Letting go of expectations
Every ayahuasca journey is unique. What unfolds may not match what you’ve heard or imagined. Once you drink, it becomes your ayahuasca—meeting you where you are, often working with deeper layers or parts of you that you may not be fully aware of. It tends to bring what is needed, not always what is expected. Letting go of fixed ideas allows you to stay open, grounded, and receptive—before, during, and after the ceremony.


i. Practical logistics
Be aware to travel with flexibility in mind. Follow the pack-list instructions from the retreat center. When possible block off a full day (or more) before and after the retreat for rest and reflection.


'Ayahuasca told me...'

During ceremony, many people receive what feel like profound messages or callings - perhaps to radically change your life, become a shaman or healer, or embark on a profound spiritual path. While these insights can be valuable seeds for reflection, be cautious about taking them as literal instructions.

The ceremony state creates a unique window where your unconscious mind, spiritual longings, and the ayahuasca effects blend together. What feels like a direct message from ayahuasca is actually arising through your own consciousness and inner wisdom.
Discerning ceremony insights
Give it time - Let insights mature before acting on them. Major 'callings' often need months of integration to reveal their true meaning
Look for confirmation - True insights typically resurface in daily life through synchronicities, dreams, or gradual unfolding, not just as one-time pronouncements
Consider pre-existing desires - Ask yourself honestly if this 'calling' reflects something you secretly desired before ceremony
Seek perspective - Discuss significant messages with the facilitator or an experienced integration specialists who can help distinguish genuine guidance from ego inflation
Reframe the narrative - Instead of 'Ayahuasca told me to...', try e.g. 'During ceremony, I gained clarity about...' This subtle shift acknowledges both the ayahuasca's role and your own agency

Remember that authentic (spiritual) growth rarely demands dramatic announcements to others or immediate identity changes. True wisdom often manifests quietly through consistent, humble practice and gradual transformation in how you move through the world.

2. Navigation: The ceremony
a. Re-mindings through the journey
This journey is yours—personal, unpredictable, and never quite like anyone else’s. There’s no right way to experience ayahuasca.

Stay hydrated throughout the ceremony.

When a follow-up dose is offered, listen to your body. Don’t decide based on what others do. Some people need more, others are complete with one cup. Trust your own rhythm.

Bring a notebook. Writing things down can be deeply valuable for integration. Use it for notetaking—simply capturing what arises. Making sense of it (notemaking) can come later, when things have settled. Let the experience unfold first, and give it meaning afterwards.

Also, avoid comparing your process with others. Each person walks their own path. Whether your experience is soft or intense, clear or mysterious—it’s not better or worse. It’s yours.


b. Mutual clarity
Any responsible retreat centre will include a personal interview beforehand and an explanation of the ‘flight instructions’—the practical and psychological guidelines to help you navigate the ceremony. Be honest when answering their questions, be curious, and don’t hesitate to ask anything you’re unsure about. Respect the safety agreements; they exist to protect the well-being of everyone involved and help create a safe and sacred space for both yourself and others.


c. Drinking and settling in
The general advice is to drink on an empty stomach—no solid food for 4 to 6 hours before. This helps the body receive the ayahuasca more clearly and can reduce early discomfort. That said, some more experienced participants have found that a small amount of food—some fruit or a light soup—can help them feel more grounded. Listen to what your body needs. If you’re unsure, it’s best to start with an empty stomach. You’ll find your own balance with time.

Drink the ayahuasca consciously—whether you sip slowly or drink it all at once—perhaps with your intention in mind, then let it go. If your stomach feels unsettled just after drinking, try to keep it in for a little while if you can.

After drinking, follow the ceremonial rhythm, or simply make yourself comfortable. Let go of expectations, and don’t try to steer the experience. You’re not here to make something happen—you’re here to allow something to move.

Avoid waiting for the ayahuasca to 'kick in.' Ayahuasca works in its own way, on its own timing—and 'waiting' often gets in the way. Just breathe, embrace the silence, the nature, or the music, stay connected to your body, and let the process unfold.


d. To purge or not to purge
Purging is a natural part of the ayahuasca process. It can come as vomiting, yawning, sweating, crying, shaking, diarrhoea, or laughter—often accompanied by a deep emotional and somatic release. It’s the body and psyche letting go of what no longer needs to be held.

You may notice different parts of yourself surfacing—some ready to release, others holding on. There’s no need to fight the purge, suppress it, or try to be stronger than it. Let it move through you. Surrender often brings relief.

Purging can leave you with a sense of clarity, calm, or lightness. It helps clear physical tension, emotional weight, or old patterns stored in the body. Just breathe, stay connected to yourself, and let the process unfold—at its own pace and with its own force.


e. Navigating visions and communicating with ayahuasca
Ayahuasca often communicates through symbols, images, and sensations rather than words. These visions may appear as vivid visuals, emotional insights, or sensory experiences. Stay receptive and curious rather than trying to control what emerges.
If you wish to communicate with the plant, you might:
  • Ask simple, open questions in your mind: 'What do I need to learn?' or 'Please help me understand...'
  • Listen deeply, allowing responses to emerge naturally through feelings, images, or sudden knowing
  • Express gratitude for any guidance received, whether clear or mysterious

Acceptance and reappraisal
Whatever arises in your ceremony—whether visions, sensations, or difficult emotions—practice acceptance first. Allow the experience to be exactly as it is, without immediately trying to change or interpret it.
Later, as the journey unfolds, gentle reappraisal may emerge naturally: 'What might this be showing me?' or 'How can I meet this challenge differently?' This isn't analysis in the analytical sense, but rather a felt sense of finding new perspectives within the experience itself.

Remember that ayahuasca often works beneath the surface of conscious awareness. If visions don't arise, or if they seem confusing, trust that the plant is working in ways beyond what you can perceive. Sometimes the most profound teachings come through silence, darkness, or subtle shifts in your body and breath.

f. When things get intense
Even the bravest among you can feel overwhelmed. If strong emotions or sensations rise up, try not to resist. Breathe slowly, through your nose. Let the breath anchor you in your body.

If you need support, reach out—sometimes a hand on your shoulder, a grounding song, or a quiet moment aside is enough to help you find your centre again.

Remember: no feeling lasts forever. Whatever moves through you will also pass. You don’t need to understand it in the moment—just stay with it, and let it unfold.
Psychedelic integration is the process of actively turning insights and experiences from your psychedelic journey into meaningful changes in your daily life. It involves using agency to reflect upon, understand, and apply these experiences over days, weeks, and months afterward. Integration helps you translate moments of clarity into personal growth, healthier habits, and lasting well-being.
3. Integration: bring your 'work' into everyday life
Here begins the most essential, meaningful, and fulfilling part of your journey: Integration.
The integration process starts even before the ceremony itself, through intentional preparation. Setting clear intentions and preparing yourself mentally and emotionally lays important groundwork. Integration continues throughout the ceremony, as you consciously navigate your experience and capture insights along the way.
However, the deepest and most transformative integration typically unfolds in the days, weeks, and months following your ceremony. This period, often called the 'afterglow', is a special window of increased openness and neuroplasticity—a time when your brain is especially receptive to forming new patterns. Your nervous system may feel more sensitive, your mind more flexible, and your heart more attuned. This heightened openness is both a valuable opportunity and a responsibility. What you intentionally practice and focus on during this sensitive period—mentally, emotionally, and behaviorally—is more likely to solidify into lasting positive change.
Yet, integration does not end here. Ultimately, it is an ongoing, lifelong journey of consciously embedding these insights and new ways of being into your everyday life. The patterns you nurture now have the potential to profoundly shape your future.

You are the author of your own process, and the following reflections are invitations—take what resonates and explore at your own pace. When you notice points repeated throughout this guide, these overlaps indicate areas that many find particularly important in their integration journey.


a. To support your integration process you might consider
Be kind to yourself - Treat yourself well in all senses
Be mindful of patterns – Notice when old habits creep back in. Don’t judge them, just choose gently
Stay close to what matters – Let your actions reflect what you’ve touched in the ceremony
Keep it simple – Small, regular steps are more powerful than dramatic changes
Tap into integration circles – Both online and in-person groups can offer non-judgmental sharing, shared lived wisdom, and practical tips you won’t always get in a one-on-one setting
Work with a guide or therapist if needed – Integration is not always easy, and support can make a difference



b. Additional practices to support your neuroplastic window of opportunity
Be intentional with your attention - What you focus on during this time may be strengthened more easily. Direct your awareness toward what you wish to cultivate
Create consistent routines - Regular, repeated engagement with new practices helps strengthen neural pathways more effectively than occasional efforts
Reduce unnecessary stress - Research suggests that chronic stress can impair neuroplasticity. Finding balance between processing and rest supports optimal integration
Honor your sleep - Quality sleep is crucial for consolidating new neural connections and insights from your experience
Embrace novelty - Trying new experiences or engaging with challenges can help maintain brain flexibility and openness to change
Recognize the time-sensitive nature - The neuroplastic effects may be strongest in the first days to weeks after your ceremony, making this period particularly valuable for establishing new patterns.
Try an integration log - Each end of your day, write down what practice you did and how it felt or what shifted. This helps you spot which habits truly support your integration and which might need tweaking


c. Practises for integration
These suggestions can help you stay grounded and maximize your experience. Consider starting with what feels most relevant to you and expanding from there
Spent time in nature - This is considered one of the most nourishing activities after a psychedelic journey
Listen to your body - Check in with yourself: What does your body need today? It could be rest, nourishment, hydration, movement, or simply a moment of stillness. Activities like massage, yoga and sauna might feel supportive. Notice what helps you feel connected and grounded
Revisiting your experience - Taking time to reflect on impactful moments from the workshop can be grounding. You might find it helpful to meditate or listen to the music from the ceremony
Journal your thoughts - Writing about your thoughts, feelings, or dreams can be a powerful integration tool
Get creative - Engaging in art, music, or other creative outlets might help you explore your experience in new ways. Allow yourself to express yourself freely without judgement
Practice self-care - Prioritise self-care in ways that feel right for you. This might include quality sleep, nourishing food, or taking time for yourself
Be present - Mindfulness practices might help you stay grounded in the present moment. Observe what brings you into the ‘now’ throughout your day
Cultivate gratitude - Take a moment each day to reflect on what you're grateful for. This practice can help maintain a positive perspective
Connect with others - If it feels right, share your experience with trusted friends or loved ones. Consider joining integration circles or practices
Take action steps - Challenge yourself to choose one or two concrete commitments—whether it's a dietary shift, new creative project, or communication boundary—that honor your ceremony's teachings. Revisit these intentions weekly to prevent insights from fading

d. When reuniting with loved ones
When reuniting with loved ones, remember they haven't shared your experience. Partners often silently wonder if you still love them and if you're still the same person.
If your love remains strong, express this warmly. For relationship insights that emerged during ceremony, consider the context:
  • For healthy relationships experiencing new doubts, give yourself the full integration period (about two months) before making decisions.
  • For relationships with pre-existing issues where the ceremony brought clarity, you might act sooner - but still take some time to ground yourself first. Consider whether these insights confirmed what you already knew or represent entirely new revelations.
In either case, avoid attributing decisions solely to 'Ayahuasca told me...' and share your experiences gradually, allowing conversations to unfold naturally. The key is discernment - distinguishing between insights that need time to mature and those that simply confirmed what you already knew but weren't ready to acknowledge.
Remember that integration is personal - there's no single correct timeline for everyone.


e. Additional helpful tips
Create ceremony anniversaries - Mark your calendar to revisit and reflect on your experience after 1, 3, and 6 months, allowing insights to unfold at different stages
Practice 'micro-integrations' - Set brief, daily 2-3 minute check-ins with yourself to reconnect with ceremony insights
Pay attention to your dreams - The post-ceremony period often brings vivid or meaningful dreams that can offer additional insights
Use anchoring techniques - Create physical reminders like a bracelet or stone that you can touch to reconnect with your ceremony insights
Approach insights with humility - Some of the most profound wisdom reveals itself gradually over time rather than immediately

f. Somethings to be aware of
Allow mystery - Allow the ineffable aspects to remain mysterious; not everything needs intellectual analysis
Honour your unique journey - Your journey is unique; comparing your process to others' can create unnecessary pressure
Be aware of spiritual bypassing - Acknowledge that genuine transformation includes facing difficult emotions, not just focusing on 'love and light'
Value subtle as much as intense - Dramatic emotional releases aren't necessarily more valuable than subtle shifts in perspective
Cultivate practices that truly resonates with you - Find authentic ways to nurture your insights rather than adopting practices that don't feel genuine to you
Be mindful about media consumption - Create a protective space for your sensitive state by choosing information sources consciously
Watch for patterns you've outgrown - Notice when old behaviors resurface and whether they still serve your evolving self, especially in relationships
Be mindful of substances that might cloud clarity - Alcohol and other psychoactives may dim the residual glow of insights still integrating
Engage actively with your experience - Honor the journey by dedicating conscious effort to working with what you've received
Let major insights mature before action - Give significant revelations time to settle, seeking reflection and diverse perspectives before reshaping your life
Hold messages with gentle discernment - Receive wisdom with an open heart while allowing it to unfold through your lived experience
Remember, it's normal to feel a range of emotions after a retreat or a workshop. Integration is a personal journey, and there's no single 'correct' approach. If you encounter challenges or have questions, don't hesitate to reach out to your facilitator or retreat center or someone you trust for support.

g. When integration presents challenges
While the afterglow period offers profound opportunities for growth, it’s essential to understand that not all post-ceremony experiences unfold smoothly. Some journeys bring encounters with challenging experiences. You might feel energetically vulnerable or experience unexpected connections to something perceived as negative or harmful. While these phenomena can feel quite real, remember they are part of a broader landscape of consciousness exploration.

Psychological responses vary widely. Some report adverse mental health effects, including feelings of disconnection, loss of pleasure, anxiety, or depression. While many consider these part of a transformative process, incidental people seek professional support when difficulties persist. Anxiety or panic sensations are particularly common, as are experiences of feeling slightly detached from reality or your body—known as derealization and depersonalization.

Sleep patterns often shift dramatically, especially after night ceremonies. Some experience insomnia for days, while others find themselves revisiting the journey state during dreams, waking with intense sensations, frightening imagery, or a feeling of losing their grip on reality. These sleep disturbances can intensify anxiety and complicate integration further.

Your worldview might undergo profound shifts. While beneficial transformation can occur, it sometimes leads to existential struggles as you attempt to reconcile new insights with everyday life. This 'ontological shock', a profound disruption in one’s worldview causing intense existential confusion or distress, can leave you grappling to understand your place in the world.

Be especially mindful of spiritual bypassing—using spiritual experiences to avoid addressing practical life issues. Similarly, hastily acting on perceived messages—especially 'callings' to become a shaman, healer or dramatically change your life—often stems from ego inflation or 'guruism', rather than authentic guidance.

Having supportive structures matters deeply. Without grounding community support or understanding practitioners, returning to ordinary life can feel isolating. Seeking informed, professional support familiar with psychedelic integration is crucial for managing lasting difficulties. Practices like meditation, mindfulness, journaling, acupuncture, dietary adjustments, and physical grounding activities may also significantly aid in your integration.


If you notice these unpleasant patterns emerging

Document your experiences without judgment

Connect with others who understand these states

• Seek professional support specifically trained in psychedelic integration


Remember: seeking support when integration becomes challenging is wisdom, not weakness. Every journey serves its purpose, and with proper care and informed support, even the most difficult experiences can become pathways to deeper understanding.

Integration is the art of bringing ceremony into your life


What science tells us
These recent systematic reviews and meta-analyses highlight ayahuasca’s potential therapeutic benefits, particularly in addressing depression, anxiety, PTSD, and substance use disorders. These studies also note that ayahuasca may influence personality traits, such as increasing openness and self-transcendence, which could contribute to its therapeutic effects. However, while the findings are promising, researchers emphasize the need for more rigorous, controlled studies to fully understand ayahuasca’s efficacy and safety profiles.
Systematic Review on Ayahuasca and Psychological Disorders (2024)
Authors: Sheth, A., et al.

Summary: This review focused on ayahuasca’s effects on mental health conditions such as depression, anxiety, PTSD, substance abuse, and eating disorders, analyzing 43 studies published between 2017 and 2023.

Key Findings: The review underscores ayahuasca’s potential as a therapeutic tool, particularly when considering the ritualistic and “mystical” aspects of its use, though it notes limitations due to the reliance on self-reported data.

Read the full article
Systematic Review on Therapeutic Effects of Ayahuasca (2023)
Authors: Gonçalves, J., Luís, Â., Gallardo, E., & Duarte, A.P

Summary: This comprehensive review analyzed 66 peer-reviewed studies up to December 2022, highlighting ayahuasca’s potential benefits in treating depression, anxiety, neurobiological disorders, and its anti-inflammatory and antimicrobial properties.

Key Findings: The studies suggest significant therapeutic potential, though they also emphasize the need for more rigorous clinical trials to confirm these effects.

Read the full article
Systematic Review and Meta-Analysis on Ayahuasca and Personality Traits (2022)
Author: Apud, I.

Summary: This study examined the relationship between long-term ayahuasca use and personality traits, providing insights into how ayahuasca may influence aspects like openness and conscientiousness.

Key Findings: The analysis suggests that ayahuasca use is associated with certain personality changes, though the authors call for more longitudinal studies to better understand these effects.

Read the full article


Ayahuasca (ceremonial) contexts
Below are the main types of ayahuasca-style ceremonies. Between these types there can be overlap, and there exists a whole spectrum of ceremony styles, including those from indigenous groups such as the Yawanawá and Huni Kuin, whose traditions have become more visible through recent intercultural exchange.

Besides choosing a context, it is essential to thoroughly research the reputation of facilitators or groups through references and trustable sources. A title or self-designation such as 'shaman' offers no guarantee of safety, authenticity, or ethical conduct.
Traditional indigenous shamanism
Rooted in Amazonian tribes such as the Shipibo-Konibo and Urarina, ayahuasca ceremonies are led by shamans (ayahuasqueros) who use icaros (sacred songs), tobacco, and other rituals to facilitate healing and spiritual guidance.

These practices are deeply intertwined with the community’s cosmology and ancestral traditions.


Syncretic religious traditions
In Brazil, syncretic religions like Santo Daime and União do Vegetal (UDV) incorporate ayahuasca (referred to as “Daime” or “Hoasca”) into Christian-inspired rituals.

These ceremonies blend elements of Catholicism, Spiritism, and Afro-Brazilian religions, often conducted in structured, church-like settings with hymns and formal attire.
Neo-shamanic
This modern adaptation is often favourable to Western participants seeking personal or spiritual growth experiences. Settings are often more comfortable than those used in shamanic-style ceremonies and more culturally accessible for Western participants.

Ceremonies often blend elements from various traditions and are conducted by facilitators or self-identified shamans.
Therapeutic and clinical settings
Modern therapeutic approaches can involve the use of ayahuasca in controlled environments, often facilitated by psychologists or medically trained professionals. While some maintain ceremonial elements, others focus primarily on the clinical application.

These psychedelic-assisted sessions focus on mental health treatment, including addressing depression, PTSD, and addiction, emphasising integration and aftercare.

Essential (re)sources
Explore a curated selection of authoritative books, documentaries, indigenous organisations and scientific/academic institutes. Spanning philosophical treatises, integration guides, ethnographic research, and firsthand accounts, this chronological guide balances indigenous wisdom with modern science—perfect for researchers, practitioners, and curious seekers alike.
Book publications
  1. Ayahuasca as Liquid Divinity: An Ontological Approach
  • Author: André van der Braak
  • Publication: May 15, 2023
  • Publisher: Lexington Books (Studies in Comparative Philosophy and Religion)
  • ISBN: 978-1-66690-644-8 (hardcover), 978-1-66690-645-5 (eBook)
  • Focus: Philosophical analysis of ayahuasca's Western adoption
  • Summary: Van der Braak argues that ayahuasca religiosity is ultimately not about individual recreation or healing, or even personal visions, but rather about engaging in communal transformative ecodelic practices that let us work as companions of the gods in order to practice solidarity with all sentient beings.
  1. Psychedelic Integration: Psychotherapy for Non-Ordinary States of Consciousness
  • Author: Marc B. Aixalà
  • Publication: August 23, 2022
  • Publisher: Synergetic Press
  • ISBN: 978-0907791393
  • Focus: Psychedelic integration methods and practices
  • Summary: Marc B. Aixalà traces the evolution of psychedelic-assisted therapy and integration research from the 1960s to the present moment, explains therapeutic techniques and outlines a clinician’s real-world observations on the deep work of healing.
  1. The Fellowship of the River: A Medical Doctor's Exploration into Traditional Amazonian Plant Medicine
  • Author: Joseph Tafur, MD
  • Publication: March 10, 2017
  • Publisher: Espiritu Books (self-published)
  • ISBN: 978-0-9986095-0-8
  • Focus: Bridging Amazonian shamanism and Western medicine
  • Summary: A Colombian-American physician recounts his apprenticeship with Amazonian healers. He describes patients' stories where ayahuasca helped address trauma, chronic illness, and emotional pain, illustrating mind-body healing from a medical perspective.
  1. Ayahuasca Reader: Encounters with the Amazon's Sacred Vine
  • Editors: Luis Eduardo Luna & Steven F. White
  • Publication: 2016 (expanded 2nd ed.)
  • Publisher: Synergetic Press
  • ISBN: 978-0907791591
  • Focus: Anthology of ayahuasca writings
  • Summary: A comprehensive collection of essays, interviews, and indigenous stories about ayahuasca. Contributors include ethnobotanists, anthropologists, healers, and artists, offering insights into the ritual use, spirituality, and science of the sacred brew.
  1. Ayahuasca Shamanism in the Amazon and Beyond
  • Editors: Beatriz Caiuby Labate & Clancy Cavnar
  • Publication: 2014
  • Publisher: Oxford University Press
  • ISBN: 978-0199341207
  • Focus: Anthropological perspectives on globalized shamanism
  • Summary: This academic anthology brings together leading researchers exploring the globalization of ayahuasca shamanism, its various cultural expressions, and the intersection of traditional practices with modern contexts. The collection examines the complex cultural exchanges occurring as ayahuasca use expands beyond the Amazon into global settings.
  1. Ayahuasca: Rituals, Potions and Visionary Art from the Amazon
  • Authors: Arno Adelaars, Claudia Müller-Ebeling & Christian Rätsch
  • Publication: November 29, 2016
  • Publisher: Divine Arts
  • ISBN: 978-1611250510
  • Focus: Ethnobotany and visionary art
  • Summary: This richly illustrated book combines ethnobotanical information, cultural context, and visual analysis of ayahuasca art and symbolism. It documents how ayahuasca visions have influenced artistic expression across cultures and provides comprehensive information on the history, chemistry, and traditional uses of ayahuasca.
  1. Ayahuasca in My Blood: 25 Years of Medicine Dreaming
  • Author: Peter Gorman
  • Publication: May 8, 2010
  • Publisher: Lulu.com (reprint edition)
  • ISBN: 978-0557469208
  • Focus: Memoir of decades of ayahuasca exploration
  • Summary: Journalist Peter Gorman shares 25 years of journeys in the Peruvian Amazon drinking ayahuasca. He recounts his apprenticeship with indigenous curanderos, profound healing experiences, and challenges faced integrating visionary teachings into daily life. Offers a candid, personal look at long-term work with the medicine.
  1. Singing to the Plants: A Guide to Mestizo Shamanism in the Upper Amazon
  • Author: Stephan V. Beyer, PhD
  • Publication: June 2010 (paperback; first ed. 2009)
  • Publisher: University of New Mexico Press
  • ISBN: 978-0826347305
  • Focus: Mestizo shamanism in the Amazon
  • Summary: A detailed ethnographic study of how Amazonian healers work with ayahuasca and plant spirits. Beyer, an anthropologist trained in mestizo vegetalismo, describes icaros (sacred songs), healing rituals, and the complex relationship between shamans, spirits, and the jungle pharmacy.
  1. The Antipodes of the Mind: Charting the Phenomenology of the Ayahuasca Experience
  • Author: Benny Shanon
  • Publication: January 23, 2003
  • Publisher: Oxford University Press
  • ISBN: 978-0199252930
  • Focus: Cognitive psychology of the ayahuasca experience
  • Summary: An Israeli psychologist documents over 100 ayahuasca sessions, analyzing common visions, themes, and cognitive effects. This scholarly work maps the phenomenology of ayahuasca – from imagery and insights to altered sense of time – and theorizes about its impact on the mind.
  1. The Cosmic Serpent: DNA and the Origins of Knowledge
  • Author: Jeremy Narby, PhD
  • Publication: 1998
  • Publisher: Jeremy P. Tarcher/Putnam
  • ISBN: 978-0874779110
  • Focus: Bridging indigenous knowledge and science
  • Summary: An anthropologist proposes that ayahuasca visions and shamanic knowledge symbolically communicate real information about DNA and biology. He recounts his fieldwork with Amazonian shamans and suggests that ayahuasca's serpentine visions could represent microscopic biological truths, sparking debate between science and mysticism.

Documentaries
1. Antidote
Director: Marc Silver
Release: 2023
Runtime: 78 minutes
Focus: Tourism, colonialism, and ecological healing
Summary: This documentary examines the complex intersection of ayahuasca tourism, colonial history, and ecological healing. It explores questions of cultural appropriation alongside ayahuasca's potential role in addressing both personal and planetary healing in a time of environmental crisis.
Perspective: Takes a critical, nuanced approach to the globalization of ayahuasca, offering perspectives from indigenous practitioners, Western seekers, and environmental activists.
2. How to Change Your Mind
Director: Lucy Walker & Alison Ellwood
Release: 2022
Runtime: 53 minutes (Episode 4: "Ayahuasca")
Focus: Scientific, historical, and cultural exploration
Summary: The fourth episode of Michael Pollan's Netflix docuseries examines ayahuasca's traditional use and growing mainstream acceptance. Featuring interviews with researchers, practitioners, and participants, it balances scientific inquiry with personal accounts of healing and transformation.
Perspective: Presents ayahuasca within the context of the broader psychedelic renaissance, emphasizing both its therapeutic potential and the importance of respecting its traditional contexts.


3. The Medicine
Director: Farzin Toussi
Release: 2019
Runtime: 85 minutes
Focus: Healing journey with indigenous context
Summary: This documentary follows former NFL player Kerry Rhodes as he travels to the Amazon to experience ayahuasca with Shipibo healers. The film explores ayahuasca's traditional indigenous use as well as its potential therapeutic applications, featuring interviews with researchers, practitioners, and indigenous leaders.
Perspective: Balanced presentation that honors indigenous traditions while examining ayahuasca's growing appeal to Westerners seeking alternative healing modalities.
4. From Shock to Awe
Director: Luc Côté
Release: 2019
Runtime: 87 minutes
Focus: Therapeutic use for PTSD and trauma
Summary: An intimate documentary about two U.S. combat veterans with severe PTSD who attend ayahuasca ceremonies (and other psychedelic therapy) to heal their trauma. It documents their emotional breakthroughs and struggles with integration back home.
Perspective: Focuses on therapeutic outcomes for Western veterans, highlighting ayahuasca's capacity to address trauma while stressing the importance of proper support and aftercare.
5. The Nature of Ayahuasca
Director: Gavin Hoffman

Release: 2019

Runtime: 95 minutes

Focus: Holistic medicine and community healing Summary: This documentary explores ayahuasca through the lens of holistic medicine, featuring compelling testimonials from community members who have experienced profound healing. The film balances personal transformation stories with broader cultural and ecological contexts.

Perspective: Takes a holistic view that honors both the individual healing journey and the communal, ecological dimensions of ayahuasca traditions.

Link: https://www.imdb.com/title/tt10826054/

6. The Last Shaman
Director: Raz Degan
Release: 2016
Runtime: 77 minutes
Focus: Western seekers and mental health
Summary: This documentary follows a young American man with depression who travels to Peru as a last resort to work with ayahuasca healers. It candidly shows both irresponsible "ayahuasqueros" and genuine shamans he encounters.
Perspective: A Western seeker's journey that avoids sensationalism by addressing mental health, cultural respect, and the potential as well as pitfalls of the ayahuasca healing process.
7. Embrace of the Serpent
Director: Ciro Guerra
Release: 2015
Runtime: 125 minutes
Focus: Indigenous cosmology and colonial impact
Summary: A black-and-white dramatic film following an Amazonian shaman who guides two Western explorers (in 1909 and 1940) in search of a sacred plant. Based on true travel diaries, it authentically portrays indigenous cosmology and the effects of colonial contact.
Perspective: Centers indigenous knowledge and spirituality (including ayahuasca use) with lyrical, respectful storytelling.
8. Aya: Awakenings
Directors: Timothy Parish & Rak Razam
Release: 2013
Runtime: 89 minutes
Focus: Journalistic exploration of Peruvian ayahuasca culture
Summary: A hybrid documentary-drama based on Rak Razam's travelogue. It combines real footage and reenactments to chronicle an Australian journalist's deep immersion into Peru's ayahuasca culture. Viewers witness shamanic ceremonies, visionary experiences, and interviews with curanderos and Western experts.
Perspective: Blends Western outsider and indigenous viewpoints – while visually immersive, it remains informative about ayahuasca's context and emphasizes respectful exploration over hype.
9. The Shaman & Ayahuasca
Director: Michael Wiese
Release: 2010
Runtime: 72 minutes
Focus: Traditional mestizo healing practices
Summary: A documentary featuring Peruvian curandero Don José Campos, who explains ayahuasca rituals and teachings. The filmmaker undergoes ceremonies under Campos's guidance, capturing visions and insights on camera.
Perspective: Offers an indigenous mestizo healer's perspective on ayahuasca medicine. The tone is informative and reverent, avoiding drama – viewers learn about icaros (sacred songs), dieta, and the spiritual philosophy behind the healing practice.

Indigenous organizations & initiatives

1. Indigenous Reciprocity Initiative of the Americas (IRI)
IRI, incubated by Chacruna, focuses specifically on ensuring that the benefits of the psychedelic renaissance are shared with indigenous communities. It directly addresses crucial ethical considerations of reciprocity, conservation, and cultural preservation, making it a foundational resource for ethical engagement with ayahuasca.

Highlights: Projects supporting indigenous communities, biocultural conservation, fair-trade models, and resources for ethical engagement.

Link: https://chacruna-iri.org/program/


2. Indigenous Medicine Conservation Fund (IMC Fund)
The IMC Fund is an indigenous-led nonprofit dedicated to protecting and preserving traditional plant medicines (including ayahuasca, iboga, peyote, etc.) and the indigenous cultures that steward them. They work to counter biopiracy, overharvesting, and cultural appropriation by directly funding Indigenous-led conservation projects and advocating for Indigenous rights and knowledge.

Highlights: Their mission to support indigenous-led conservation, ethical sourcing, cultural protection, and the well-being of communities connected to sacred plant medicines. They are a critical resource for understanding ethical engagement.
3. COICA (Coordinadora de las Organizaciones Indígenas de la Cuenca Amazónica / Coordinator of Indigenous Organizations of the Amazon Basin)
COICA is the largest indigenous umbrella organization representing indigenous peoples across the nine Amazonian countries. They are a powerful voice for indigenous rights, territorial defense, and the protection of ancestral knowledge and biodiversity, which directly includes plant medicines like ayahuasca.
Highlights: Advocacy for indigenous rights, territorial protection, cultural preservation, and environmental conservation in the Amazon. Their work indirectly but powerfully supports the contexts where ayahuasca traditions thrive.

4. UMIYAC (Unión de Médicos Indígenas Yageceros del Putumayo - Union of Indigenous Yagé Doctors of Putumayo, Colombia)
UMIYAC comprises indigenous elders and traditional doctors who work with Yagé (ayahuasca) to heal communities, particularly those affected by conflict and addiction. They are a significant voice for ethical use and the protection of ancestral knowledge in Colombia.
Highlights: Ancestral medicine for peace, community healing, spiritual revitalization, addressing social issues through traditional practices.

Scientific/Academic resources (journals & organizations)

1. MAPS (Multidisciplinary Association for Psychedelic Studies)
MAPS is a leading non-profit organization researching and advocating for the medical and spiritual uses of psychedelics, including ayahuasca. Their website is a treasure trove of research, news, and educational materials.

Highlights: Clinical trials, policy updates, educational resources, published articles.

Link: https://maps.org/


2. ICEERS (International Center for Ethnobotanical Education, Research, and Service)
ICEERS focuses specifically on psychedelics and ethnobotanicals, with a strong emphasis on risk reduction, public health, and cultural integration. They have a dedicated section on ayahuasca.

Highlights: Research, policy work, harm reduction guidelines, legal information.

Link: https://www.iceers.org/


3. Chacruna (Institute for Psychedelic Plant Medicines)
Chacruna is a highly respected non-profit organization that provides education and promotes cultural understanding and reciprocity in the psychedelic space, with a strong focus on ayahuasca and other plant medicines. They offer articles, events, and resources from diverse perspectives, including indigenous voices.

Highlights: Articles on ethics, cultural appropriation, traditional uses, legal aspects, and diverse perspectives from scholars and practitioners.

Link: https://chacruna.net/


4. Kahpi (an ayahuasca hub)
Kahpi is a dedicated online encyclopedia for ayahuasca, aiming to be a comprehensive and accessible source of information on its history, chemistry, cultural uses, and therapeutic applications. It can be a valuable resource for those seeking detailed explanations on various aspects of ayahuasca.

Highlights: In-depth articles on specific topics related to ayahuasca, its compounds, traditional practices, and modern applications.

Link: https://kahpi.net/


5. Journal of Psychedelic Studies
JPS is a peer-reviewed academic journal that often features research on ayahuasca, offering rigorous scientific and scholarly articles.

Highlights: Specific research articles, methodologies, and scientific findings related to psychedelics.

Link: https://akajournals.com/jps


Ayahuasca: A visual journey
From its natural habitat, through preparation, to ceremonial consumption and a contemporary room setting




Some 'famous' quotes
While scientific research and traditional knowledge provide important foundations, these personal reflections from public figures offer additional perspectives on the ayahuasca experience.
Sting (musician)
“It’s not a frivolous pursuit. There’s a certain amount of dread attached to taking it because it’s not entertaining. You have a sense that you’re going to face something that’s truthful rather than recreational.”
Lindsay Lohan (actress)
“I did ayahuasca, it changed my life… I saw my whole life in front of me, and I had to let go of past things. It was intense.”
Paul Simon (musician)
“I drank a cup of herbal brew, the sweetness in the air, combined with the lightness in my head, and I heard the jungle breathing in the bamboo.”
Dr. Gabor Maté (physician)
"Ayahuasca shows you yourself, not as you pretend to be, but as you actually are. That's why it's both difficult and deeply healing."

Ayahuasca, is it calling you?
Ayahuasca can offer deep transformation, but it requires careful consideration. Ayahuasca is not merely a transformation tool, but a sacred plant teacher and tradition that connects participants to eclectic spiritual wisdom, plant intelligence, and communal ritual practices that have evolved through South American lineages for generations.
A 25-question assessment helps you explore your mindset and readiness, discover your preparedness for this inner journey, and provides you with a personalised report.

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