Longer-form pieces on the science, law, and lived experience of ayahuasca — researched, referenced, and written to inform your own discernment.
Rini Hartman
Summary: Two 2025–26 trials moved DMT into clinical neuroscience — one reducing brain damage after stroke in animal models, the other the first placebo-controlled trial of intravenous DMT for major depression — while a parallel line of research examines the full brew itself.
Key points: In stroke models DMT protects the brain via sigma-1 receptors, separate from the 5-HT₂A pathway behind the visionary effect, raising the prospect of sub-psychedelic dosing. A single intravenous dose eased depression within a week and lasted months, with the brew’s harmala alkaloids and the post-experience plasticity window adding further potential.
Read the full articleRini Hartman
Summary: The same brew is regulated in some countries and prosecuted as trafficking in others. Drawing on the contrasting Dutch and Canadian frameworks, the piece asks whether legal systems can create narrow, conditional routes for regulated use under enforceable safety conditions.
Key points: International treaties control DMT but not the plants or traditional preparations, yet national courts have split, from Spanish acquittals to the Dutch Supreme Court’s prohibition. Canada’s Section 56 “public interest” exemption shows regulated access can work; the Netherlands has a structurally similar system but lacks the open ground to use it.
Read the full articleRini Hartman
Summary: Many people receive what feel like profound messages or callings in ceremony. This shorter piece offers a way to hold them — as valuable seeds for reflection rather than literal instructions.
Key points: What feels like a direct message arises through your own consciousness and inner wisdom; give it time, and look for confirmation in daily life before acting. Reframing “Ayahuasca told me to…” as “In ceremony I gained clarity about…” honours both the brew’s role and your own agency.
Read the full articleThis page offers honest, balanced and serious information about ayahuasca. It is not an invitation to drink nor a substitute for a proper medical assessment or for the specific guidance of a qualified facilitator.
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